Growth factor receptor-bound protein 2 promotes autophagic removal of amyloid-ß protein precursor intracellular domain overload in neuronal cells.

Roy, Kasturi; Raychaudhuri, Mithu; Chakrabarti, Oishee; Mukhopadhyay, Debashis

Roy, Kasturi; Raychaudhuri, Mithu; Chakrabarti, Oishee; Mukhopadhyay, Debashis.

Affiliation

Roy K; Biophysics and Structural Genomics Division, Saha Institute of Nuclear Physics, WB, Kolkata, India.

J Alzheimers Dis ; 38(4): 881-95, 2014.

Article in En | MEDLINE | ID: mdl-24100123

Subject(s)

Amyloid beta-Protein Precursor/metabolism; Autophagy/physiology; GRB2 Adaptor Protein/physiology; Intracellular Fluid/metabolism; Neurons/metabolism; Amyloid beta-Protein Precursor/toxicity; Animals; Cell Line, Tumor; GRB2 Adaptor Protein/toxicity; Humans; Neurons/pathology

Key words

Amyloid-ß protein precursor protein; CD63; Grb2; LC3 protein; autophagy; clathrin; dynamin

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Autophagy / Amyloid beta-Protein Precursor / GRB2 Adaptor Protein / Intracellular Fluid / Neurons Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: J Alzheimers Dis Journal subject: GERIATRIA / NEUROLOGIA Year: 2014 Document type: Article Affiliation country: India

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