Codelivery of curcumin and doxorubicin by MPEG-PCL results in improved efficacy of systemically administered chemotherapy in mice with lung cancer.

Wang, Bi-Lan; Shen, Yong-mei; Zhang, Qiong-wen; Li, Yu-li; Luo, Min; Liu, Ze; Li, Yan; Qian, Zhi-yong; Gao, Xiang; Shi, Hua-shan

Wang, Bi-Lan; Shen, Yong-mei; Zhang, Qiong-wen; Li, Yu-li; Luo, Min; Liu, Ze; Li, Yan; Qian, Zhi-yong; Gao, Xiang; Shi, Hua-shan.

Affiliation

Wang BL; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, West China Medicine School, Sichuan University, Chengdu, Sichuan, People's Republic of China.

Int J Nanomedicine ; 8: 3521-31, 2013.

Article in En | MEDLINE | ID: mdl-24101869

Subject(s)

Antineoplastic Combined Chemotherapy Protocols/administration & dosage; Antineoplastic Combined Chemotherapy Protocols/chemical synthesis; Lung Neoplasms/drug therapy; Nanocapsules/administration & dosage; Nanocapsules/chemistry; Polyesters/chemistry; Polyethylene Glycols/chemistry; Animals; Cell Line, Tumor; Curcumin/administration & dosage; Curcumin/chemistry; Doxorubicin/administration & dosage; Doxorubicin/chemistry; Female; Injections, Intravenous; Lung Neoplasms/pathology; Mice; Mice, Inbred C57BL; Micelles; Nanocapsules/ultrastructure; Particle Size; Treatment Outcome

Key words

cancer; curcumin; doxorubicin; methoxy poly(ethylene glycol); micelles; poly(caprolactone); treatment

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Polyesters / Polyethylene Glycols / Antineoplastic Combined Chemotherapy Protocols / Nanocapsules / Lung Neoplasms Limits: Animals Language: En Journal: Int J Nanomedicine Year: 2013 Document type: Article

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