Cardiac rehabilitation and outcome in stable outpatients with recent myocardial infarction.
Arch Phys Med Rehabil
; 95(2): 322-9, 2014 Feb.
Article
in En
| MEDLINE
| ID: mdl-24121084
ABSTRACT
OBJECTIVE:
To compare the mortality rate and the rate of subsequent ischemic events (myocardial infarction [MI], ischemic stroke, or limb amputation) in patients with recent MI according to the use of cardiac rehabilitation or no rehabilitation.DESIGN:
Longitudinal observational study.SETTING:
Ongoing registry of outpatients.PARTICIPANTS:
Patients (N=1043) with recent acute MI were recruited; of these, 521 (50%) participated in cardiac rehabilitation.INTERVENTIONS:
Not applicable. MAIN OUTCOMEMEASURES:
Subsequent ischemic events and mortality rates were registered.RESULTS:
Over a mean follow-up of 18 months, 50 patients (4.8%) died and 49 (4.7%) developed 52 subsequent ischemic events (MI n=43, ischemic stroke n=6, limb amputation n=3). Both the mortality rate (.16 vs 5.57 deaths per 100 patient-years; rate ratio=.03; 95% confidence interval [CI], 0.0-0.1]) and the rate of subsequent ischemic events (1.65 vs 4.54 events per 100 patient-years; rate ratio=0.4; 95% CI, 0.2-0.7) were significantly lower in cardiac rehabilitation participants than in nonparticipants. Multivariate analysis confirmed that patients in cardiac rehabilitation had a significantly lower risk of death (hazard ratio=.08; 95% CI, .01-.63; P=.016) and a nonsignificant lower risk of subsequent ischemic events (hazard ratio=.65; 95% CI, .30-1.42).CONCLUSIONS:
The use of cardiac rehabilitation in patients with recent MI was independently associated with a significant decrease in the mortality rate and a nonsignificant decrease in the rate of subsequent ischemic events.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Myocardial Infarction
Type of study:
Etiology_studies
/
Observational_studies
/
Risk_factors_studies
Limits:
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Language:
En
Journal:
Arch Phys Med Rehabil
Year:
2014
Document type:
Article