Synthesis and evaluation of new polynuclear organometallic Ru(II), Rh(III) and Ir(III) pyridyl ester complexes as in vitro antiparasitic and antitumor agents.

Chellan, Prinessa; Land, Kirkwood M; Shokar, Ajit; Au, Aaron; An, Seung Hwan; Taylor, Dale; Smith, Peter J; Riedel, Tina; Dyson, Paul J; Chibale, Kelly; Smith, Gregory S

Chellan, Prinessa; Land, Kirkwood M; Shokar, Ajit; Au, Aaron; An, Seung Hwan; Taylor, Dale; Smith, Peter J; Riedel, Tina; Dyson, Paul J; Chibale, Kelly; Smith, Gregory S.

Affiliation

Chellan P; Department of Chemistry, University of Cape Town, Private Bag, Rondebosch 7701, South Africa. gregory.smith@uct.ac.za.

Dalton Trans ; 43(2): 513-26, 2014 Jan 14.

Article in En | MEDLINE | ID: mdl-24121555

Subject(s)

Antineoplastic Agents/chemical synthesis; Antineoplastic Agents/pharmacology; Antiparasitic Agents/chemical synthesis; Antiparasitic Agents/pharmacology; Organometallic Compounds/chemical synthesis; Organometallic Compounds/pharmacology; Pyridines/chemistry; Antineoplastic Agents/chemistry; Antiparasitic Agents/chemistry; Cell Line, Tumor; Chemistry Techniques, Synthetic; Humans; Iridium/chemistry; Models, Molecular; Molecular Conformation; Organometallic Compounds/chemistry; Plasmodium falciparum/drug effects; Rhodium/chemistry; Ruthenium/chemistry; Solubility; Trichomonas vaginalis/drug effects

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Organometallic Compounds / Pyridines / Antineoplastic Agents / Antiparasitic Agents Limits: Humans Language: En Journal: Dalton Trans Journal subject: QUIMICA Year: 2014 Document type: Article Affiliation country: South Africa Country of publication: United kingdom

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