Development of thiolated poly(acrylic acid) microparticles for the nasal administration of exenatide.

Millotti, Gioconda; Vetter, Anja; Leithner, Katharina; Sarti, Federica; Shahnaz Bano, Gul; Augustijns, Patrick; Bernkop-Schnürch, Andreas

Millotti, Gioconda; Vetter, Anja; Leithner, Katharina; Sarti, Federica; Shahnaz Bano, Gul; Augustijns, Patrick; Bernkop-Schnürch, Andreas.

Affiliation

Millotti G; Department of Pharmaceutical Technology, Institute of Pharmacy, Leopold-Franzens-University Innsbruck, CCB-Center for Chemistry and Biochemistry , Innsbruck, Austria , Europe and.

Drug Dev Ind Pharm ; 40(12): 1677-82, 2014 Dec.

Article in En | MEDLINE | ID: mdl-24131355

Subject(s)

Acrylic Resins/administration & dosage; Microspheres; Particle Size; Peptides/administration & dosage; Sulfhydryl Compounds/administration & dosage; Venoms/administration & dosage; Acrylic Resins/pharmacokinetics; Administration, Intranasal; Animals; Cells, Cultured; Exenatide; Humans; Nasal Mucosa/drug effects; Nasal Mucosa/metabolism; Peptides/pharmacokinetics; Sulfhydryl Compounds/pharmacokinetics; Swine; Venoms/pharmacokinetics

Key words

Exenatide; microparticles; nasal delivery; thiolated polymers

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Particle Size / Peptides / Sulfhydryl Compounds / Venoms / Acrylic Resins / Microspheres Limits: Animals / Humans Language: En Journal: Drug Dev Ind Pharm Year: 2014 Document type: Article Country of publication: United kingdom

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