Human cytomegalovirus UL97 kinase is involved in the mechanism of action of methylenecyclopropane analogs with 6-ether and -thioether substitutions.

Komazin-Meredith, Gloria; Chou, Sunwen; Prichard, Mark N; Hartline, Caroll B; Cardinale, Steven C; Comeau, Katelyn; Williams, John D; Khan, Atiyya R; Peet, Norton P; Bowlin, Terry L

Komazin-Meredith, Gloria; Chou, Sunwen; Prichard, Mark N; Hartline, Caroll B; Cardinale, Steven C; Comeau, Katelyn; Williams, John D; Khan, Atiyya R; Peet, Norton P; Bowlin, Terry L.

Affiliation

Komazin-Meredith G; Microbiotix Inc., Worcester, Massachusetts, USA.

Antimicrob Agents Chemother ; 58(1): 274-8, 2014.

Article in En | MEDLINE | ID: mdl-24145545

Subject(s)

Antiviral Agents/chemistry; Antiviral Agents/pharmacology; Cyclopropanes/chemistry; Cyclopropanes/pharmacology; Cytomegalovirus/drug effects; Cytomegalovirus/enzymology; Ether/chemistry; Sulfides/chemistry; Cell Line; Humans

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Antiviral Agents / Sulfides / Cyclopropanes / Cytomegalovirus / Ether Limits: Humans Language: En Journal: Antimicrob Agents Chemother Year: 2014 Document type: Article Affiliation country: United States Country of publication: United States

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