The 4 Notch receptors play distinct and antagonistic roles in the proliferation and hepatocytic differentiation of liver progenitors.

Ortica, Sara; Tarantino, Nadine; Aulner, Nathalie; Israël, Alain; Gupta-Rossi, Neetu

Ortica, Sara; Tarantino, Nadine; Aulner, Nathalie; Israël, Alain; Gupta-Rossi, Neetu.

Affiliation

Ortica S; 1Unité de Signalisation Moléculaire et Activation Cellulaire, URA 2582 CNRS, Institut Pasteur, 25 rue du Dr Roux, 75724 Paris Cedex 15, France. neetu.gupta@pasteur.fr.

FASEB J ; 28(2): 603-14, 2014 Feb.

Article in En | MEDLINE | ID: mdl-24145721

Subject(s)

Hepatocytes/cytology; Hepatocytes/metabolism; Liver/cytology; Liver/metabolism; Receptors, Notch/metabolism; Stem Cells/cytology; Stem Cells/metabolism; Animals; Cell Differentiation/genetics; Cell Differentiation/physiology; Cell Line; Cell Proliferation; Fluorescent Antibody Technique; Mice; Real-Time Polymerase Chain Reaction; Receptors, Notch/genetics

Key words

CDK inhibitors; bipotential stem cells; hepatoblasts; paralogs; polyploidy

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Stem Cells / Hepatocytes / Receptors, Notch / Liver Limits: Animals Language: En Journal: FASEB J Journal subject: BIOLOGIA / FISIOLOGIA Year: 2014 Document type: Article Affiliation country: France Country of publication: United States

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