Antagonism of brain insulin-like growth factor-1 receptors blocks estradiol effects on memory and levels of hippocampal synaptic proteins in ovariectomized rats.

Nelson, Britta S; Springer, Rachel C; Daniel, Jill M

Nelson, Britta S; Springer, Rachel C; Daniel, Jill M.

Affiliation

Nelson BS; Neuroscience Program, Tulane University, New Orleans, LA, 70118, USA.

Psychopharmacology (Berl) ; 231(5): 899-907, 2014 Mar.

Article in En | MEDLINE | ID: mdl-24146138

Subject(s)

Oligopeptides/pharmacology; Receptor, IGF Type 1/antagonists & inhibitors; Animals; Disks Large Homolog 4 Protein; Estradiol/pharmacology; Estrogen Antagonists/pharmacology; Female; Guanylate Kinases/metabolism; Hippocampus/drug effects; Hippocampus/metabolism; Intracellular Signaling Peptides and Proteins/metabolism; Maze Learning/drug effects; Membrane Proteins/metabolism; Memory/drug effects; Microfilament Proteins/metabolism; Nerve Tissue Proteins/metabolism; Rats; Rats, Long-Evans; Receptor, IGF Type 1/metabolism; Spatial Navigation/drug effects; Synapses/drug effects; Synapses/metabolism; Synaptophysin/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Oligopeptides / Receptor, IGF Type 1 Limits: Animals Language: En Journal: Psychopharmacology (Berl) Year: 2014 Document type: Article Affiliation country: United States Country of publication: Germany

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