Endogenous human MDM2-C is highly expressed in human cancers and functions as a p53-independent growth activator.

Okoro, Danielle R; Arva, Nicoleta; Gao, Chong; Polotskaia, Alla; Puente, Cindy; Rosso, Melissa; Bargonetti, Jill

Okoro, Danielle R; Arva, Nicoleta; Gao, Chong; Polotskaia, Alla; Puente, Cindy; Rosso, Melissa; Bargonetti, Jill.

Affiliation

Okoro DR; Department of Biological Sciences Hunter College and The Graduate Center Departments of Biology and Biochemistry, City University of New York, New York City, United States of America.

PLoS One ; 8(10): e77643, 2013.

Article in En | MEDLINE | ID: mdl-24147044

Subject(s)

Neoplasms/metabolism; Protein Isoforms/metabolism; Proto-Oncogene Proteins c-mdm2/metabolism; Tumor Suppressor Protein p53/metabolism; Blotting, Northern; Blotting, Western; Cell Line, Tumor; Fluorescent Antibody Technique; Humans; Immunohistochemistry; Immunoprecipitation; Microscopy, Confocal; Neoplasms/genetics; Protein Isoforms/genetics; Proto-Oncogene Proteins c-mdm2/genetics; Reverse Transcriptase Polymerase Chain Reaction; Tumor Suppressor Protein p53/genetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tumor Suppressor Protein p53 / Protein Isoforms / Proto-Oncogene Proteins c-mdm2 / Neoplasms Limits: Humans Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2013 Document type: Article Affiliation country: United States Country of publication: United States

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