Implementation of cardovascular cell therapy network trials: challenges, innovation and lessons learned from experience in the CCTRN.
Expert Rev Cardiovasc Ther
; 11(11): 1495-502, 2013 Nov.
Article
in En
| MEDLINE
| ID: mdl-24147517
ABSTRACT
The cardiovascular cell therapy network was developed by the National Heart, Lung and Blood Institute to design and conduct clinical trials to advance the field of cardiovascular (CV) cell-based therapy. The Cardiovascular Cell Therapy Network successfully completed three clinical trials involving approximately 300 subjects across five centers and six satellites. Although the concept of a network within clinical trials research is not new, the knowledge gained in the implementation of such large-scale trials, particularly in novel therapeutic areas such as cell therapy is not often detailed in the literature. The purpose of this communication is to summarize key factors in achieving network goals and share the knowledge gained to promote success in future cardiovascular disease cell therapy trials and networks.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Cardiovascular Diseases
/
Clinical Trials as Topic
/
Cell- and Tissue-Based Therapy
Limits:
Humans
Country/Region as subject:
America do norte
Language:
En
Journal:
Expert Rev Cardiovasc Ther
Journal subject:
ANGIOLOGIA
/
CARDIOLOGIA
/
TERAPEUTICA
Year:
2013
Document type:
Article
Affiliation country:
United States