S-adenosylmethionine limitation induces p38 mitogen-activated protein kinase and triggers cell cycle arrest in G1.

Lin, Da-Wei; Chung, Benjamin P; Kaiser, Peter

Lin, Da-Wei; Chung, Benjamin P; Kaiser, Peter.

Affiliation

Lin DW; University of California Irvine, Department of Biological Chemistry, College of Medicine, 240D Med Sci I, Irvine, CA 92697-1700, USA.

J Cell Sci ; 127(Pt 1): 50-9, 2014 Jan 01.

Article in En | MEDLINE | ID: mdl-24155332

Subject(s)

B-Lymphocytes/metabolism; Cell Cycle Checkpoints/genetics; G1 Phase/genetics; Mitogen-Activated Protein Kinase 14/genetics; S-Adenosylmethionine/deficiency; B-Lymphocytes/cytology; Cell Line, Tumor; Cyclin E/genetics; Cyclin E/metabolism; Cyclin-Dependent Kinase 2/genetics; Cyclin-Dependent Kinase 2/metabolism; Cyclin-Dependent Kinase 4/genetics; Cyclin-Dependent Kinase 4/metabolism; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation; Humans; Intracellular Signaling Peptides and Proteins/genetics; Intracellular Signaling Peptides and Proteins/metabolism; Mechanistic Target of Rapamycin Complex 1; Methionine/deficiency; Methionine Adenosyltransferase/genetics; Methionine Adenosyltransferase/metabolism; Mitogen-Activated Protein Kinase 14/metabolism; Multiprotein Complexes/genetics; Multiprotein Complexes/metabolism; Phosphorylation; Protein Serine-Threonine Kinases/genetics; Protein Serine-Threonine Kinases/metabolism; Signal Transduction; TOR Serine-Threonine Kinases/genetics; TOR Serine-Threonine Kinases/metabolism

Key words

Cell cycle; MAPKAPK2; MK2; One carbon cycle; S-adenosylmethionine; SAM; p38 MAPK

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: S-Adenosylmethionine / B-Lymphocytes / G1 Phase / Mitogen-Activated Protein Kinase 14 / Cell Cycle Checkpoints Limits: Humans Language: En Journal: J Cell Sci Year: 2014 Document type: Article Affiliation country: United States Country of publication: United kingdom

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google