D-lactic acidosis: an unusual cause of encephalopathy in a patient with short bowel syndrome.
Acta Clin Belg
; 68(3): 229-31, 2013.
Article
in En
| MEDLINE
| ID: mdl-24156228
ABSTRACT
A 24-year-old woman with a short bowel syndrome following post-ischemic small bowel resection, developed several episodes of lethargy, echolalia and ataxia. D-lactic acidosis was identified as the cause of neurological disturbances. This infrequent disorder can be precipitated by intake of a large amount of sugars, in patients with short bowel syndrome. It should be suspected in the presence of metabolic acidosis with increased anion gap and a normal level of L-lactic acid. The diagnosis relies on the specific dosage of D-lactic stereoisomer. Proper management involves rehydration, diet adaptation and oral administration of poorly absorbed antibiotics in order to modify the colonic flora responsible for D-lactic production.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Short Bowel Syndrome
/
Acidosis, Lactic
/
Brain Diseases
Type of study:
Prognostic_studies
Limits:
Adult
/
Female
/
Humans
Language:
En
Journal:
Acta Clin Belg
Year:
2013
Document type:
Article
Affiliation country:
Belgium