Insights into the carboxyltransferase reaction of pyruvate carboxylase from the structures of bound product and intermediate analogs.

Lietzan, Adam D; St Maurice, Martin

Lietzan, Adam D; St Maurice, Martin.

Affiliation

Lietzan AD; Department of Biological Sciences, Marquette University, Milwaukee, WI 53201, USA.

Biochem Biophys Res Commun ; 441(2): 377-82, 2013 Nov 15.

Article in En | MEDLINE | ID: mdl-24157795

Subject(s)

Carboxyl and Carbamoyl Transferases/chemistry; Plant Proteins/chemistry; Pyruvate Carboxylase/chemistry; Rhizobium etli/enzymology; Carboxyl and Carbamoyl Transferases/antagonists & inhibitors; Crystallography, X-Ray; Enzyme Inhibitors/chemistry; Oxalates/chemistry; Protein Structure, Tertiary; Pyruvate Carboxylase/antagonists & inhibitors; Pyruvates/chemistry; Substrate Specificity

Key words

2-[Bis(2-hydroxyethyl)amino]-2-(hydroxymethyl)propane-1,3-diol; APS; BC; BCCP; Biotin-dependent carboxylase; BisTris; CT; Carboxyltransferase; LS-CAT; Life Sciences Collaborative Access Team; PC; PEG; Pyruvate carboxylase; RePC; Rhizobium etli pyruvate carboxylase; SaPC; Staphylococcus aureus pyruvate carboxylase; TMACl; advanced photon source; biotin carboxyl carrier protein; biotin carboxylase; carboxyl transferase; poly(ethylene glycol); pyruvate carboxylase; tetramethylammonium chloride

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Plant Proteins / Pyruvate Carboxylase / Carboxyl and Carbamoyl Transferases / Rhizobium etli Language: En Journal: Biochem Biophys Res Commun Year: 2013 Document type: Article Affiliation country: United States Country of publication: United States

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