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Targeted degradation of sense and antisense C9orf72 RNA foci as therapy for ALS and frontotemporal degeneration.
Lagier-Tourenne, Clotilde; Baughn, Michael; Rigo, Frank; Sun, Shuying; Liu, Patrick; Li, Hai-Ri; Jiang, Jie; Watt, Andrew T; Chun, Seung; Katz, Melanie; Qiu, Jinsong; Sun, Ying; Ling, Shuo-Chien; Zhu, Qiang; Polymenidou, Magdalini; Drenner, Kevin; Artates, Jonathan W; McAlonis-Downes, Melissa; Markmiller, Sebastian; Hutt, Kasey R; Pizzo, Donald P; Cady, Janet; Harms, Matthew B; Baloh, Robert H; Vandenberg, Scott R; Yeo, Gene W; Fu, Xiang-Dong; Bennett, C Frank; Cleveland, Don W; Ravits, John.
Affiliation
  • Lagier-Tourenne C; Departments of Neurosciences, Cellular and Molecular Medicine, and Pathology, and Ludwig Institute for Cancer Research, University of California, San Diego, La Jolla, CA 92093.
Proc Natl Acad Sci U S A ; 110(47): E4530-9, 2013 Nov 19.
Article in En | MEDLINE | ID: mdl-24170860
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Genetic Therapy / Proteins / Oligonucleotides, Antisense / DNA Repeat Expansion / Frontotemporal Lobar Degeneration / Amyotrophic Lateral Sclerosis Type of study: Prognostic_studies Limits: Animals Language: En Journal: Proc Natl Acad Sci U S A Year: 2013 Document type: Article Country of publication: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Genetic Therapy / Proteins / Oligonucleotides, Antisense / DNA Repeat Expansion / Frontotemporal Lobar Degeneration / Amyotrophic Lateral Sclerosis Type of study: Prognostic_studies Limits: Animals Language: En Journal: Proc Natl Acad Sci U S A Year: 2013 Document type: Article Country of publication: United States