Oral absorption enhancement of salmon calcitonin by using both N-trimethyl chitosan chloride and oligoarginines-modified liposomes as the carriers.

Huang, Aiwen; Su, Zhigui; Li, Sai; Sun, Minjie; Xiao, Yanyu; Ping, Qineng; Deng, Yanping

Huang, Aiwen; Su, Zhigui; Li, Sai; Sun, Minjie; Xiao, Yanyu; Ping, Qineng; Deng, Yanping.

Affiliation

Huang A; Department of Pharmacy, Fuzhou General Hospital, Nanjing Military Command , Fuzhou , China .

Drug Deliv ; 21(5): 388-96, 2014 Aug.

Article in En | MEDLINE | ID: mdl-24188463

Subject(s)

Arginine/chemistry; Calcitonin/chemistry; Chitosan/chemistry; Drug Carriers/chemistry; Intestinal Absorption/drug effects; Liposomes/chemistry; Administration, Oral; Animals; Arginine/administration & dosage; Caco-2 Cells; Calcitonin/administration & dosage; Cell Line, Tumor; Chitosan/administration & dosage; Dextrans/administration & dosage; Dextrans/chemistry; Drug Carriers/administration & dosage; Fluorescein-5-isothiocyanate/administration & dosage; Fluorescein-5-isothiocyanate/analogs & derivatives; Fluorescein-5-isothiocyanate/chemistry; Humans; Intestinal Mucosa/metabolism; Liposomes/administration & dosage; Permeability; Rats; Rats, Sprague-Dawley

Key words

Liposomes; N-trimethyl chitosan chloride; oligoarginines; oral absorption enhancement; salmon calcitonin

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Arginine / Calcitonin / Drug Carriers / Chitosan / Intestinal Absorption / Liposomes Limits: Animals / Humans Language: En Journal: Drug Deliv Journal subject: FARMACOLOGIA / TERAPIA POR MEDICAMENTOS Year: 2014 Document type: Article Affiliation country: China Country of publication: United kingdom

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