CD154 is released from T-cells by a disintegrin and metalloproteinase domain-containing protein 10 (ADAM10) and ADAM17 in a CD40 protein-dependent manner.

Yacoub, Daniel; Benslimane, Nadir; Al-Zoobi, Loubna; Hassan, Ghada; Nadiri, Amal; Mourad, Walid

Yacoub, Daniel; Benslimane, Nadir; Al-Zoobi, Loubna; Hassan, Ghada; Nadiri, Amal; Mourad, Walid.

Affiliation

Yacoub D; From the Laboratoire d'Immunologie Cellulaire et Moléculaire, Centre Hospitalier de l'Université de Montréal, Hôpital St-Luc, Montréal, Quebec H2X 1P1, Canada.

J Biol Chem ; 288(50): 36083-93, 2013 Dec 13.

Article in En | MEDLINE | ID: mdl-24189063

Subject(s)

ADAM Proteins/metabolism; Amyloid Precursor Protein Secretases/metabolism; CD40 Antigens/metabolism; CD40 Ligand/metabolism; Membrane Proteins/metabolism; T-Lymphocytes/metabolism; ADAM10 Protein; ADAM17 Protein; CD40 Antigens/chemistry; Cell Line; Cell Membrane/metabolism; Enzyme Activation; Humans; Protein Kinase C/metabolism; Proteolysis; Signal Transduction; Solubility; T-Lymphocytes/cytology

Key words

CD154; CD40; Cell Signaling; Inflammation; Integrins; Molecular Biology; Receptors; T-cells

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: T-Lymphocytes / CD40 Antigens / CD40 Ligand / ADAM Proteins / Amyloid Precursor Protein Secretases / Membrane Proteins Limits: Humans Language: En Journal: J Biol Chem Year: 2013 Document type: Article Affiliation country: Canada Country of publication: United States

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