A kinetic isotope effect and isotope exchange study of the nonenzymatic and the equine serum butyrylcholinesterase-catalyzed thioester hydrolysis.

Robins, Lori I; Meisenheimer, Kristen M; Fogle, Emily J; Chaplan, Cory A; Redman, Richard L; Vacca, Joseph T; Tellier, Michelle R; Collins, Brittney R; Duong, Dorothea H; Schulz, Kathrin; Marlier, John F

Robins, Lori I; Meisenheimer, Kristen M; Fogle, Emily J; Chaplan, Cory A; Redman, Richard L; Vacca, Joseph T; Tellier, Michelle R; Collins, Brittney R; Duong, Dorothea H; Schulz, Kathrin; Marlier, John F.

Affiliation

Robins LI; Department of Chemistry and Biochemistry, California Polytechnic State University , San Luis Obispo, CA 93407.

J Org Chem ; 78(23): 12029-39, 2013 Dec 06.

Article in En | MEDLINE | ID: mdl-24224609

Subject(s)

Butyrylcholinesterase/metabolism; Deuterium Oxide/chemistry; Esters/metabolism; Sulfhydryl Compounds/metabolism; Biocatalysis; Butyrylcholinesterase/blood; Esters/chemistry; Kinetics; Molecular Structure; Oxygen Isotopes; Sulfhydryl Compounds/chemistry

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sulfhydryl Compounds / Butyrylcholinesterase / Deuterium Oxide / Esters Language: En Journal: J Org Chem Year: 2013 Document type: Article Country of publication: United States

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