The kinetics of myelin antigen uptake by myeloid cells in the central nervous system during experimental autoimmune encephalomyelitis.

Sosa, Rebecca A; Murphey, Cathi; Ji, Niannian; Cardona, Astrid E; Forsthuber, Thomas G

Sosa, Rebecca A; Murphey, Cathi; Ji, Niannian; Cardona, Astrid E; Forsthuber, Thomas G.

Affiliation

Sosa RA; Department of Biology, University of Texas at San Antonio, San Antonio, TX 78249.

J Immunol ; 191(12): 5848-57, 2013 Dec 15.

Article in En | MEDLINE | ID: mdl-24227784

Subject(s)

Antigens/metabolism; Brain/metabolism; Encephalomyelitis, Autoimmune, Experimental/metabolism; Myelin Proteolipid Protein/pharmacokinetics; Myelin-Oligodendrocyte Glycoprotein/pharmacokinetics; Myeloid Cells/metabolism; Peptide Fragments/pharmacokinetics; Spinal Cord/metabolism; Adoptive Transfer; Animals; Antigen Presentation; Antigens/immunology; Autoantibodies/biosynthesis; Autoantibodies/immunology; Brain/immunology; Cell Movement; Dendritic Cells/immunology; Dendritic Cells/metabolism; Female; Freund's Adjuvant; Imaging, Three-Dimensional; Immunization; Injections, Intraperitoneal; Injections, Subcutaneous; Lymphocyte Activation; Male; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Mice, Neurologic Mutants; Mice, Transgenic; Microglia/metabolism; Microscopy, Confocal; Myelin Basic Protein/analysis; Myelin Basic Protein/immunology; Myelin Proteolipid Protein/immunology; Myelin-Oligodendrocyte Glycoprotein/immunology; Peptide Fragments/immunology; Pertussis Toxin; Spinal Cord/immunology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Peptide Fragments / Spinal Cord / Brain / Myelin Proteolipid Protein / Myeloid Cells / Encephalomyelitis, Autoimmune, Experimental / Myelin-Oligodendrocyte Glycoprotein / Antigens Language: En Journal: J Immunol Year: 2013 Document type: Article Country of publication: United States

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