Apoptosis/drug effects; Bupivacaine/toxicity; Ginkgolides/pharmacology; Lactones/pharmacology; Neuroprotective Agents/pharmacology; Caspase 12/genetics; Caspase 12/metabolism; Caspase 3/metabolism; Cell Line, Tumor; Cell Proliferation/drug effects; Cell Shape/drug effects; Cell Shape/genetics; Cell Survival/drug effects; Cell Survival/genetics; Electron Transport Complex I/metabolism; Electron Transport Complex III/metabolism; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress/drug effects; Endoplasmic Reticulum Stress/genetics; Enzyme Activation/drug effects; Flow Cytometry; Heat-Shock Proteins/genetics; Heat-Shock Proteins/metabolism; High-Temperature Requirement A Serine Peptidase 2; Humans; Membrane Potential, Mitochondrial/drug effects; Membrane Potential, Mitochondrial/genetics; Mitochondria/drug effects; Mitochondria/metabolism; Mitochondria/ultrastructure; Mitochondrial Proteins/metabolism; RNA, Messenger/genetics; RNA, Messenger/metabolism; Reactive Oxygen Species/metabolism; Serine Endopeptidases/metabolism