Continuous hypoxic culturing of human embryonic stem cells enhances SSEA-3 and MYC levels.

Närvä, Elisa; Pursiheimo, Juha-Pekka; Laiho, Asta; Rahkonen, Nelly; Emani, Maheswara Reddy; Viitala, Miro; Laurila, Kirsti; Sahla, Roosa; Lund, Riikka; Lähdesmäki, Harri; Jaakkola, Panu; Lahesmaa, Riitta

Närvä, Elisa; Pursiheimo, Juha-Pekka; Laiho, Asta; Rahkonen, Nelly; Emani, Maheswara Reddy; Viitala, Miro; Laurila, Kirsti; Sahla, Roosa; Lund, Riikka; Lähdesmäki, Harri; Jaakkola, Panu; Lahesmaa, Riitta.

Affiliation

Närvä E; Turku Centre for Biotechnology, Turku University and Åbo Akademi University, Turku, Finland.

PLoS One ; 8(11): e78847, 2013.

Article in En | MEDLINE | ID: mdl-24236059

Subject(s)

Antigens, Tumor-Associated, Carbohydrate/metabolism; Embryonic Stem Cells/physiology; Proto-Oncogene Proteins c-myc/metabolism; Stage-Specific Embryonic Antigens/metabolism; Antigens, Tumor-Associated, Carbohydrate/genetics; Cell Differentiation; Cell Hypoxia; Cell Proliferation; Cells, Cultured; Gene Expression Regulation; Homeodomain Proteins/genetics; Homeodomain Proteins/metabolism; Humans; Nanog Homeobox Protein; Octamer Transcription Factor-3/genetics; Octamer Transcription Factor-3/metabolism; Proto-Oncogene Proteins c-myc/genetics; SOXB1 Transcription Factors/genetics; SOXB1 Transcription Factors/metabolism; Stage-Specific Embryonic Antigens/genetics; Transcriptional Activation; Transcriptome

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Antigens, Tumor-Associated, Carbohydrate / Proto-Oncogene Proteins c-myc / Embryonic Stem Cells / Stage-Specific Embryonic Antigens Limits: Humans Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2013 Document type: Article Affiliation country: Finland Country of publication: United States

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