In vivo thermal ablation monitoring using ultrasound echo decorrelation imaging.
Ultrasound Med Biol
; 40(1): 102-14, 2014 Jan.
Article
in En
| MEDLINE
| ID: mdl-24239361
ABSTRACT
Previous work indicated that ultrasound echo decorrelation imaging can track and quantify changes in echo signals to predict thermal damage during in vitro radiofrequency ablation (RFA). In the in vivo studies reported here, the feasibility of using echo decorrelation imaging as a treatment monitoring tool was assessed. RFA was performed on normal swine liver (N = 5), and ultrasound ablation using image-ablate arrays was performed on rabbit liver implanted with VX2 tumors (N = 2). Echo decorrelation and integrated backscatter were computed from Hilbert transformed pulse-echo data acquired during RFA and ultrasound ablation treatments. Receiver operating characteristic (ROC) curves were employed to assess the ability of echo decorrelation imaging and integrated backscatter to predict ablation. Area under the ROC curves (AUROC) was determined for RFA and ultrasound ablation using echo decorrelation imaging. Ablation was predicted more accurately using echo decorrelation imaging (AUROC = 0.832 and 0.776 for RFA and ultrasound ablation, respectively) than using integrated backscatter (AUROC = 0.734 and 0.494).
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Image Interpretation, Computer-Assisted
/
Ultrasonography, Interventional
/
Hepatectomy
/
Hyperthermia, Induced
/
Liver Neoplasms
Type of study:
Diagnostic_studies
/
Prognostic_studies
Limits:
Animals
Language:
En
Journal:
Ultrasound Med Biol
Year:
2014
Document type:
Article
Affiliation country:
United States