Age-related motor dysfunction and neuropathology in a transgenic mouse model of multiple system atrophy.

Fernagut, P O; Meissner, W G; Biran, M; Fantin, M; Bassil, F; Franconi, J M; Tison, F

Fernagut, P O; Meissner, W G; Biran, M; Fantin, M; Bassil, F; Franconi, J M; Tison, F.

Affiliation

Fernagut PO; Institut des Maladies Neurodégénératives, Université de Bordeaux, UMR 5293, F-33000 Bordeaux, France; CNRS, Institut des Maladies Neurodégénératives, UMR 5293, F-33000 Bordeaux, France.

Synapse ; 68(3): 98-106, 2014 Mar.

Article in En | MEDLINE | ID: mdl-24243499

Subject(s)

Brain/metabolism; Brain/pathology; Movement Disorders/metabolism; Movement Disorders/pathology; Multiple System Atrophy/metabolism; Multiple System Atrophy/pathology; Age Factors; Animals; Atrophy; Cell Death; Cerebral Ventricles/pathology; Corpus Striatum/metabolism; Corpus Striatum/pathology; Dopamine/metabolism; Humans; Magnetic Resonance Imaging; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Motor Activity; Movement Disorders/complications; Multiple System Atrophy/complications; Neuroglia/metabolism; Neuroglia/pathology; Organ Size; alpha-Synuclein/genetics; alpha-Synuclein/metabolism

Key words

alpha-synuclein; magnetic resonance imaging; motor behavior; multiple system atrophy

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Brain / Multiple System Atrophy / Movement Disorders Type of study: Prognostic_studies Limits: Animals / Humans / Male Language: En Journal: Synapse Journal subject: NEUROLOGIA Year: 2014 Document type: Article Affiliation country: France Country of publication: United States

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