The association between gall bladder mucoceles and hyperlipidaemia in dogs: a retrospective case control study.
Vet J
; 199(1): 76-9, 2014 Jan.
Article
in En
| MEDLINE
| ID: mdl-24268484
ABSTRACT
The diagnosis of gall bladder mucoceles (GM) in dogs has become increasingly frequent in veterinary medicine. Primary breed-specific hyperlipidaemia is reported in Shetland Sheepdogs and Miniature Schnauzers, breeds in which GM are known to occur more frequently than in other breeds. The objective of this study was to evaluate the association between GM and hyperlipidaemia in dogs. The study design was a retrospective case control study. Medical records of dogs diagnosed with GM at the Veterinary Medical Centre of The University of Tokyo between 1 April 2007 and 31 March 2012, were reviewed. Fifty-eight dogs with GM and a record of either serum cholesterol, triglyceride, or glucose concentrations were included in the study. Hypercholesterolaemia (15/37 cases; odds ratio [OR] 2.92; 95% confidence interval [CI] 1.02-8.36) and hypertriglyceridaemia (13/24 cases; OR 3.55; 95% CI1.12-15.91) showed significant association with GM. Pomeranians (OR 10.69), American Cocker Spaniels (OR 8.94), Shetland Sheepdogs (OR 6.21), Miniature Schnauzers (OR 5.23), and Chihuahuas (OR 3.06) were significantly predisposed to GM. Thirty-nine out of 58 cases had at least one concurrent disease, including pancreatitis (five cases), hyperadrenocorticism (two cases), and hypothyroidism (two cases). A significant association between GM and hyperlipidaemia was confirmed, suggesting that hyperlipidaemia may play a role in the pathogenesis of GM.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Dog Diseases
/
Gallbladder Diseases
/
Hyperlipidemias
/
Mucocele
Type of study:
Etiology_studies
/
Observational_studies
/
Risk_factors_studies
Limits:
Animals
Language:
En
Journal:
Vet J
Journal subject:
MEDICINA VETERINARIA
Year:
2014
Document type:
Article
Affiliation country:
Japan