Interconnectivity of sympathetic and sleep networks is mediated through reduction of gamma aminobutyric acidergic inhibition in the paraventricular nucleus.

Perry, Juliana C; Bergamaschi, Cássia T; Campos, Ruy R; Silva, Adilson M; Tufik, Sergio

Perry, Juliana C; Bergamaschi, Cássia T; Campos, Ruy R; Silva, Adilson M; Tufik, Sergio.

Affiliation

Perry JC; Department of Psychobiology, Universidade Federal de São Paulo, São Paulo, SP, Brazil.

J Sleep Res ; 23(2): 168-75, 2014 Apr.

Article in En | MEDLINE | ID: mdl-24283672

Subject(s)

Blood Pressure; Heart Rate; Paraventricular Hypothalamic Nucleus/metabolism; Sleep Deprivation/metabolism; Sleep Deprivation/physiopathology; Sympathetic Nervous System/metabolism; gamma-Aminobutyric Acid/metabolism; Animals; Bicuculline/administration & dosage; Bicuculline/pharmacology; Blood Pressure/drug effects; Down-Regulation; Heart Rate/drug effects; Kidney/innervation; Kidney/metabolism; Male; Medulla Oblongata/metabolism; Medulla Oblongata/physiopathology; Microinjections; Nitric Oxide Synthase Type I/metabolism; Paraventricular Hypothalamic Nucleus/physiology; Paraventricular Hypothalamic Nucleus/physiopathology; Random Allocation; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1/metabolism; Receptor, Angiotensin, Type 2/metabolism; Receptors, N-Methyl-D-Aspartate/metabolism; Sympathetic Nervous System/physiology; Sympathetic Nervous System/physiopathology; gamma-Aminobutyric Acid/drug effects

Key words

cardiovascular system; gamma aminobutyric acid; paraventricular nucleus; sleep; sleep restriction; sympathetic activity

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Paraventricular Hypothalamic Nucleus / Sleep Deprivation / Sympathetic Nervous System / Blood Pressure / Gamma-Aminobutyric Acid / Heart Rate Limits: Animals Language: En Journal: J Sleep Res Journal subject: PSICOFISIOLOGIA Year: 2014 Document type: Article Affiliation country: Brazil Country of publication: United kingdom

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google