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Platelet-activating factor downregulates the expression of liver X receptor-α and its target genes in human neutrophils.
Reyes-Quiroz, María E; Alba, Gonzalo; Santa-María, Consuelo; Saenz, Javier; Geniz, Isabel; Jiménez, Juan; Ramírez, Remedios; Martín-Nieto, José; Pintado, Elizabeth; Sobrino, Francisco.
Affiliation
  • Reyes-Quiroz ME; Departamento de Bioquímica Médica y Biología Molecular, Universidad de Sevilla, Spain.
FEBS J ; 281(3): 970-82, 2014 Feb.
Article in En | MEDLINE | ID: mdl-24289152
Subject(s)
Down-Regulation; Neutrophils/metabolism; Orphan Nuclear Receptors/metabolism; Platelet Activating Factor/metabolism; Platelet Membrane Glycoproteins/agonists; Receptors, G-Protein-Coupled/agonists; Signal Transduction; ATP Binding Cassette Transporter 1/agonists; ATP Binding Cassette Transporter 1/antagonists & inhibitors; ATP Binding Cassette Transporter 1/genetics; ATP Binding Cassette Transporter 1/metabolism; ATP Binding Cassette Transporter, Subfamily G, Member 1; ATP-Binding Cassette Transporters/agonists; ATP-Binding Cassette Transporters/antagonists & inhibitors; ATP-Binding Cassette Transporters/genetics; ATP-Binding Cassette Transporters/metabolism; Anticholesteremic Agents/antagonists & inhibitors; Anticholesteremic Agents/pharmacology; Antioxidants/pharmacology; Cells, Cultured; Down-Regulation/drug effects; Humans; Liver X Receptors; Lymphocytes/cytology; Lymphocytes/immunology; Lymphocytes/metabolism; Macrophages/cytology; Macrophages/immunology; Macrophages/metabolism; Neutrophil Activation/drug effects; Neutrophils/cytology; Neutrophils/drug effects; Neutrophils/immunology; Orphan Nuclear Receptors/agonists; Orphan Nuclear Receptors/antagonists & inhibitors; Orphan Nuclear Receptors/genetics; Oxidants/pharmacology; Oxidative Stress/drug effects; Phosphorylation/drug effects; Platelet Activating Factor/agonists; Platelet Activating Factor/antagonists & inhibitors; Platelet Membrane Glycoproteins/antagonists & inhibitors; Platelet Membrane Glycoproteins/metabolism; Protein Isoforms/biosynthesis; Protein Isoforms/genetics; Protein Isoforms/metabolism; Protein Processing, Post-Translational/drug effects; Receptors, G-Protein-Coupled/antagonists & inhibitors; Receptors, G-Protein-Coupled/metabolism; Signal Transduction/drug effects; Sterol Regulatory Element Binding Protein 1/agonists; Sterol Regulatory Element Binding Protein 1/antagonists & inhibitors; Sterol Regulatory Element Binding Protein 1/genetics; Sterol Regulatory Element Binding Protein 1/metabolism
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Platelet Activating Factor / Platelet Membrane Glycoproteins / Signal Transduction / Down-Regulation / Receptors, G-Protein-Coupled / Orphan Nuclear Receptors / Neutrophils Language: En Journal: FEBS J Journal subject: BIOQUIMICA Year: 2014 Document type: Article Affiliation country: Spain
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Platelet Activating Factor / Platelet Membrane Glycoproteins / Signal Transduction / Down-Regulation / Receptors, G-Protein-Coupled / Orphan Nuclear Receptors / Neutrophils Language: En Journal: FEBS J Journal subject: BIOQUIMICA Year: 2014 Document type: Article Affiliation country: Spain