Mammalian target of rapamycin complex I (mTORC1) activity in ras homologue enriched in brain (Rheb)-deficient mouse embryonic fibroblasts.

Groenewoud, Marlous J; Goorden, Susan M I; Kassies, Jorien; Pellis-van Berkel, Wendy; Lamb, Richard F; Elgersma, Ype; Zwartkruis, Fried J T

Groenewoud, Marlous J; Goorden, Susan M I; Kassies, Jorien; Pellis-van Berkel, Wendy; Lamb, Richard F; Elgersma, Ype; Zwartkruis, Fried J T.

Affiliation

Groenewoud MJ; Molecular Cancer Research, Centre for Biomedical Genetics and Cancer Genomics Centre, University Medical Center Utrecht, Utrecht, The Netherlands.

PLoS One ; 8(11): e81649, 2013.

Article in En | MEDLINE | ID: mdl-24303063

Subject(s)

Fibroblasts/metabolism; Monomeric GTP-Binding Proteins/deficiency; Multiprotein Complexes/metabolism; Neuropeptides/deficiency; TOR Serine-Threonine Kinases/metabolism; Adaptor Proteins, Signal Transducing/metabolism; Animals; Cell Line; Female; Gene Expression; Mechanistic Target of Rapamycin Complex 1; Mice; Mice, Knockout; Monomeric GTP-Binding Proteins/genetics; Multiprotein Complexes/antagonists & inhibitors; Neuropeptides/genetics; Pregnancy; RNA Interference; Ras Homolog Enriched in Brain Protein; Regulatory-Associated Protein of mTOR; Sirolimus/pharmacology; TOR Serine-Threonine Kinases/antagonists & inhibitors

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Neuropeptides / Monomeric GTP-Binding Proteins / Multiprotein Complexes / TOR Serine-Threonine Kinases / Fibroblasts Limits: Animals / Pregnancy Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2013 Document type: Article Affiliation country: Netherlands Country of publication: United States

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