Intermittent hypoxia can aggravate motor neuronal loss and cognitive dysfunction in ALS mice.

Kim, Sung-Min; Kim, Heejaung; Lee, Jeong-Seon; Park, Kyung Seok; Jeon, Gye Sun; Shon, Jeeheun; Ahn, Suk-Won; Kim, Seung Hyun; Lee, Kyung Min; Sung, Jung-Joon; Lee, Kwang-Woo

Kim, Sung-Min; Kim, Heejaung; Lee, Jeong-Seon; Park, Kyung Seok; Jeon, Gye Sun; Shon, Jeeheun; Ahn, Suk-Won; Kim, Seung Hyun; Lee, Kyung Min; Sung, Jung-Joon; Lee, Kwang-Woo.

Affiliation

Kim SM; Department of Neurology, Seoul National University, College of Medicine, Seoul, Korea.

PLoS One ; 8(11): e81808, 2013.

Article in En | MEDLINE | ID: mdl-24303073

Subject(s)

Amyotrophic Lateral Sclerosis/metabolism; Amyotrophic Lateral Sclerosis/pathology; Hypoxia/metabolism; Motor Neurons/metabolism; Motor Neurons/pathology; Amyotrophic Lateral Sclerosis/physiopathology; Animals; Disease Models, Animal; Female; Inflammation/metabolism; Inflammation/pathology; Male; Mice; Muscle Strength; Oxidative Stress; Psychomotor Performance; Rotarod Performance Test; Signal Transduction

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Amyotrophic Lateral Sclerosis / Hypoxia / Motor Neurons Type of study: Prognostic_studies Limits: Animals Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2013 Document type: Article Country of publication: United States

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