Expression of the homeobox gene HOXA9 in ovarian cancer induces peritoneal macrophages to acquire an M2 tumor-promoting phenotype.

Ko, Song Yi; Ladanyi, Andras; Lengyel, Ernst; Naora, Honami

Ko, Song Yi; Ladanyi, Andras; Lengyel, Ernst; Naora, Honami.

Affiliation

Ko SY; Department of Molecular and Cellular Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas.
Ladanyi A; Section of Gynecologic Oncology, the Department of Obstetrics and Gynecology, University of Chicago, Chicago, Illinois.
Lengyel E; Section of Gynecologic Oncology, the Department of Obstetrics and Gynecology, University of Chicago, Chicago, Illinois.
Naora H; Department of Molecular and Cellular Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas. Electronic address: hnaora@mdanderson.org.

Am J Pathol ; 184(1): 271-81, 2014 Jan.

Article in En | MEDLINE | ID: mdl-24332016

Subject(s)

Homeodomain Proteins/biosynthesis; Homeodomain Proteins/metabolism; Macrophages, Peritoneal/metabolism; Ovarian Neoplasms/immunology; Ovarian Neoplasms/metabolism; Ovarian Neoplasms/pathology; Animals; Cell Line, Tumor; Chromatin Immunoprecipitation; Disease Progression; Enzyme-Linked Immunosorbent Assay; Female; Flow Cytometry; Gene Expression Regulation, Neoplastic; Heterografts; Homeodomain Proteins/genetics; Homeodomain Proteins/immunology; Humans; Immunohistochemistry; Macrophages, Peritoneal/immunology; Mice; Mice, Nude; Phenotype; Reverse Transcriptase Polymerase Chain Reaction

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ovarian Neoplasms / Macrophages, Peritoneal / Homeodomain Proteins Type of study: Prognostic_studies Limits: Animals / Female / Humans Language: En Journal: Am J Pathol Year: 2014 Document type: Article Country of publication: United States

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