Inhibition of catechol-O-methyltransferase by 6,7-dihydroxy-3,4-dihydroisoquinolines related to dopamine: demonstration using liquid chromatography and a novel substrate for O-methylation.

Cheng, B Y; Origitano, T C; Collins, M A

Cheng, B Y; Origitano, T C; Collins, M A.

J Neurochem ; 48(3): 779-86, 1987 Mar.

Article in En | MEDLINE | ID: mdl-2433397

Subject(s)

Catechol O-Methyltransferase Inhibitors; Dopamine/analogs & derivatives; Papaverine/analogs & derivatives; Tetrahydropapaveroline/analogs & derivatives; 3,4-Dihydroxyphenylacetic Acid/metabolism; Animals; Chromatography, Liquid; Corpus Striatum/drug effects; Corpus Striatum/metabolism; Homovanillic Acid/metabolism; Hydrogen-Ion Concentration; Hydroxyindoleacetic Acid/metabolism; Hydroxylation; Hypothalamus/drug effects; Hypothalamus/metabolism; Isoquinolines/metabolism; Isoquinolines/pharmacology; Liver/enzymology; Male; Methylation; Rats; Rats, Inbred Strains; Spectrophotometry; Tetrahydropapaveroline/metabolism; Tetrahydropapaveroline/pharmacology

Search on Google

Add to My VHL

XML

PubMed Links

Collection: 01-internacional Database: MEDLINE Main subject: Papaverine / Tetrahydropapaveroline / Dopamine / Catechol O-Methyltransferase Inhibitors Limits: Animals Language: En Journal: J Neurochem Year: 1987 Document type: Article

Search on Google

Add to My VHL

XML

PubMed Links