Otx2 cell-autonomously determines dorsal mesencephalon versus cerebellum fate independently of isthmic organizing activity.

Di Giovannantonio, Luca G; Di Salvio, Michela; Omodei, Daniela; Prakash, Nilima; Wurst, Wolfgang; Pierani, Alessandra; Acampora, Dario; Simeone, Antonio

Di Giovannantonio, Luca G; Di Salvio, Michela; Omodei, Daniela; Prakash, Nilima; Wurst, Wolfgang; Pierani, Alessandra; Acampora, Dario; Simeone, Antonio.

Affiliation

Di Giovannantonio LG; Institute of Genetics and Biophysics "Adriano Buzzati-Traverso", CNR, Via P. Castellino 111, 80131 Naples, Italy.

Development ; 141(2): 377-88, 2014 Jan.

Article in En | MEDLINE | ID: mdl-24335253

Subject(s)

Cerebellum/embryology; Cerebellum/metabolism; Mesencephalon/embryology; Mesencephalon/metabolism; Otx Transcription Factors/metabolism; Animals; Body Patterning; Cell Differentiation; Embryonic Stem Cells/cytology; Embryonic Stem Cells/metabolism; Female; Mice; Mice, Knockout; Mice, Mutant Strains; Mice, Transgenic; Mutation; Neural Stem Cells/cytology; Neural Stem Cells/metabolism; Neurogenesis; Organizers, Embryonic/embryology; Organizers, Embryonic/metabolism; Otx Transcription Factors/deficiency; Otx Transcription Factors/genetics; PAX7 Transcription Factor/metabolism; Pregnancy; Transcription Factors/deficiency; Transcription Factors/genetics; Transcription Factors/metabolism

Key words

Cerebellum; Dorsal mesencephalon; Mouse; Otx2; Progenitor fate

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Mesencephalon / Cerebellum / Otx Transcription Factors Limits: Animals / Pregnancy Language: En Journal: Development Journal subject: BIOLOGIA / EMBRIOLOGIA Year: 2014 Document type: Article Affiliation country: Italy Country of publication: United kingdom

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