Identification of sphingolipid metabolites that induce obesity via misregulation of appetite, caloric intake and fat storage in Drosophila.

Walls, Stanley M; Attle, Steve J; Brulte, Gregory B; Walls, Marlena L; Finley, Kim D; Chatfield, Dale A; Herr, Deron R; Harris, Greg L

Walls, Stanley M; Attle, Steve J; Brulte, Gregory B; Walls, Marlena L; Finley, Kim D; Chatfield, Dale A; Herr, Deron R; Harris, Greg L.

Affiliation

Walls SM; Department of Biology and Molecular Biology Institute, San Diego State University, San Diego, California, United States of America.

PLoS Genet ; 9(12): e1003970, 2013.

Article in En | MEDLINE | ID: mdl-24339790

Subject(s)

Ceramides/metabolism; Lysophospholipids/metabolism; Metabolic Syndrome/genetics; Obesity/metabolism; Sphingosine/analogs & derivatives; Adipose Tissue/metabolism; Adiposity/genetics; Animals; Appetite/genetics; Chromatography, Liquid; Disease Models, Animal; Drosophila melanogaster; Energy Intake/genetics; Humans; Metabolic Syndrome/metabolism; Metabolic Syndrome/pathology; Mutation; Obesity/pathology; Oligonucleotide Array Sequence Analysis/methods; Spectrometry, Mass, Electrospray Ionization; Sphingosine/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sphingosine / Lysophospholipids / Ceramides / Metabolic Syndrome / Obesity Type of study: Diagnostic_studies Limits: Animals / Humans Language: En Journal: PLoS Genet Journal subject: GENETICA Year: 2013 Document type: Article Affiliation country: United States Country of publication: United States

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