Altered transition metal homeostasis in Niemann-Pick disease, type C1.

Hung, Ya Hui; Faux, Noel G; Killilea, David W; Yanjanin, Nicole; Firnkes, Sally; Volitakis, Irene; Ganio, George; Walterfang, Mark; Hastings, Caroline; Porter, Forbes D; Ory, Daniel S; Bush, Ashley I

Hung, Ya Hui; Faux, Noel G; Killilea, David W; Yanjanin, Nicole; Firnkes, Sally; Volitakis, Irene; Ganio, George; Walterfang, Mark; Hastings, Caroline; Porter, Forbes D; Ory, Daniel S; Bush, Ashley I.

Affiliation

Hung YH; Oxidation Biology Unit, The Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Level 4, Kenneth Myer Building, Parkville, Victoria 3010, Australia. ashley.bush@florey.edu.au.

Metallomics ; 6(3): 542-53, 2014 Mar.

Article in En | MEDLINE | ID: mdl-24343124

Subject(s)

Metals/metabolism; Niemann-Pick Disease, Type C/metabolism; Transition Elements/metabolism; 1-Deoxynojirimycin/analogs & derivatives; 1-Deoxynojirimycin/therapeutic use; Animals; Brain/metabolism; Brain/pathology; Ceruloplasmin/antagonists & inhibitors; Ceruloplasmin/metabolism; Enzyme Inhibitors/therapeutic use; Female; Gene Deletion; Homeostasis; Humans; Intracellular Signaling Peptides and Proteins; Male; Metals/blood; Metals/cerebrospinal fluid; Mice; Mice, Inbred BALB C; Niemann-Pick C1 Protein; Niemann-Pick Disease, Type C/blood; Niemann-Pick Disease, Type C/cerebrospinal fluid; Niemann-Pick Disease, Type C/drug therapy; Proteins/genetics; Transition Elements/blood; Transition Elements/cerebrospinal fluid

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Transition Elements / Niemann-Pick Disease, Type C / Metals Type of study: Clinical_trials / Prognostic_studies Limits: Animals / Female / Humans / Male Language: En Journal: Metallomics Journal subject: BIOQUIMICA Year: 2014 Document type: Article Affiliation country: Australia

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