Efficacy and safety of canakinumab therapy in paediatric patients with cryopyrin-associated periodic syndrome: a single-centre, real-world experience.

Russo, Ricardo A G; Melo-Gomes, Sonia; Lachmann, Helen J; Wynne, Karen; Rajput, Kaukab; Eleftheriou, Despina; Edelsten, Clive; Hawkins, Philip N; Brogan, Paul A

Russo, Ricardo A G; Melo-Gomes, Sonia; Lachmann, Helen J; Wynne, Karen; Rajput, Kaukab; Eleftheriou, Despina; Edelsten, Clive; Hawkins, Philip N; Brogan, Paul A.

Affiliation

Russo RA; Department of Rheumatology, UCL Institute of Child Health, 30 Guilford Street, London WC1N 1EH, UK. p.brogan@ucl.ac.uk.

Rheumatology (Oxford) ; 53(4): 665-70, 2014 Apr.

Article in En | MEDLINE | ID: mdl-24352339

Subject(s)

Antibodies, Monoclonal/therapeutic use; Cryopyrin-Associated Periodic Syndromes/drug therapy; Interleukin-1beta/antagonists & inhibitors; Adolescent; Antibodies, Monoclonal, Humanized; Blood Sedimentation; C-Reactive Protein/immunology; Child; Child, Preschool; Cryopyrin-Associated Periodic Syndromes/immunology; Female; Hemoglobins/immunology; Humans; Male; Serum Amyloid A Protein/immunology; Severity of Illness Index; Treatment Outcome

Key words

CAPS; CINCA/NOMID; Muckle-Wells; autoinflammatory; canakinumab

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Interleukin-1beta / Cryopyrin-Associated Periodic Syndromes / Antibodies, Monoclonal Type of study: Observational_studies / Risk_factors_studies Aspects: Patient_preference Limits: Adolescent / Child / Child, preschool / Female / Humans / Male Language: En Journal: Rheumatology (Oxford) Journal subject: REUMATOLOGIA Year: 2014 Document type: Article Country of publication: United kingdom

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