The Nod1, Nod2, and Rip2 axis contributes to host immune defense against intracellular Acinetobacter baumannii infection.

Bist, Pradeep; Dikshit, Neha; Koh, Tse Hsien; Mortellaro, Alessandra; Tan, Thuan Tong; Sukumaran, Bindu

Bist, Pradeep; Dikshit, Neha; Koh, Tse Hsien; Mortellaro, Alessandra; Tan, Thuan Tong; Sukumaran, Bindu.

Affiliation

Bist P; Program in Emerging Infectious Diseases, Duke-NUS Graduate Medical School, Singapore.

Infect Immun ; 82(3): 1112-22, 2014 Mar.

Article in En | MEDLINE | ID: mdl-24366254

Subject(s)

Acinetobacter Infections/immunology; Acinetobacter baumannii/immunology; Immunity, Innate/immunology; Nod1 Signaling Adaptor Protein/genetics; Nod2 Signaling Adaptor Protein/genetics; Receptor-Interacting Protein Serine-Threonine Kinase 2/genetics; Acinetobacter Infections/genetics; Acinetobacter Infections/microbiology; Cell Line; Chemokines/genetics; Chemokines/immunology; Epithelial Cells/immunology; Epithelial Cells/microbiology; HEK293 Cells; Humans; Immunity, Innate/genetics; Lung/immunology; Lung/microbiology; Macrophages/immunology; Macrophages/microbiology; NF-kappa B/genetics; NF-kappa B/immunology; Nod1 Signaling Adaptor Protein/immunology; Nod2 Signaling Adaptor Protein/immunology; Receptor-Interacting Protein Serine-Threonine Kinase 2/immunology; Signal Transduction/genetics; Signal Transduction/immunology; Up-Regulation/genetics; Up-Regulation/immunology; beta-Defensins/genetics; beta-Defensins/immunology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Acinetobacter Infections / Acinetobacter baumannii / Receptor-Interacting Protein Serine-Threonine Kinase 2 / Nod1 Signaling Adaptor Protein / Nod2 Signaling Adaptor Protein / Immunity, Innate Limits: Humans Language: En Journal: Infect Immun Year: 2014 Document type: Article Affiliation country: Singapore Country of publication: United States

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