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Recombinant PNPLA3 protein shows triglyceride hydrolase activity and its I148M mutation results in loss of function.
Pingitore, Piero; Pirazzi, Carlo; Mancina, Rosellina M; Motta, Benedetta M; Indiveri, Cesare; Pujia, Arturo; Montalcini, Tiziana; Hedfalk, Kristina; Romeo, Stefano.
Affiliation
  • Pingitore P; Department BEST (Biologia, Ecologia, Scienze della Terra), Unit of Biochemistry and Molecular Biotechnology, University of Calabria, Via P. Bucci 4c, 87036 Arcavacata di Rende, Italy; Department of Chemistry and Molecular Biology, University of Gothenburg, PO Box 462, SE-405 30 Göteborg, Sweden.
  • Pirazzi C; Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Center for Cardiovascular and Metabolic Research, Wallenberg Laboratory, University of Gothenburg, Bruna Stråket, 16 SE-413 45 Göteborg, Sweden.
  • Mancina RM; Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Center for Cardiovascular and Metabolic Research, Wallenberg Laboratory, University of Gothenburg, Bruna Stråket, 16 SE-413 45 Göteborg, Sweden; Department of Medical and Surgical Sciences, Clinical Nutrition Unit, Uni
  • Motta BM; Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Center for Cardiovascular and Metabolic Research, Wallenberg Laboratory, University of Gothenburg, Bruna Stråket, 16 SE-413 45 Göteborg, Sweden; Department of Pathophysiology and Transplantation, University of Milan, F
  • Indiveri C; Department BEST (Biologia, Ecologia, Scienze della Terra), Unit of Biochemistry and Molecular Biotechnology, University of Calabria, Via P. Bucci 4c, 87036 Arcavacata di Rende, Italy.
  • Pujia A; Department of Medical and Surgical Sciences, Clinical Nutrition Unit, University Magna Graecia of Catanzaro, Viale Europa, Localitá Germaneto, 88100 Catanzaro, Italy.
  • Montalcini T; Department of Medical and Surgical Sciences, Clinical Nutrition Unit, University Magna Graecia of Catanzaro, Viale Europa, Localitá Germaneto, 88100 Catanzaro, Italy.
  • Hedfalk K; Department of Chemistry and Molecular Biology, University of Gothenburg, PO Box 462, SE-405 30 Göteborg, Sweden. Electronic address: kristina.hedfalk@chem.gu.se.
  • Romeo S; Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Center for Cardiovascular and Metabolic Research, Wallenberg Laboratory, University of Gothenburg, Bruna Stråket, 16 SE-413 45 Göteborg, Sweden; Department of Medical and Surgical Sciences, Clinical Nutrition Unit, Uni
Biochim Biophys Acta ; 1841(4): 574-80, 2014 Apr 04.
Article in En | MEDLINE | ID: mdl-24369119
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Recombinant Proteins / Hydrolases / Lipase / Membrane Proteins Limits: Humans Language: En Journal: Biochim Biophys Acta Year: 2014 Document type: Article Affiliation country: Sweden Country of publication: Netherlands
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Recombinant Proteins / Hydrolases / Lipase / Membrane Proteins Limits: Humans Language: En Journal: Biochim Biophys Acta Year: 2014 Document type: Article Affiliation country: Sweden Country of publication: Netherlands