Requirement of the Pseudomonas aeruginosa CbrA sensor kinase for full virulence in a murine acute lung infection model.

Yeung, Amy T Y; Janot, Laure; Pena, Olga M; Neidig, Anke; Kukavica-Ibrulj, Irena; Hilchie, Ashley; Levesque, Roger C; Overhage, Joerg; Hancock, Robert E W

Yeung, Amy T Y; Janot, Laure; Pena, Olga M; Neidig, Anke; Kukavica-Ibrulj, Irena; Hilchie, Ashley; Levesque, Roger C; Overhage, Joerg; Hancock, Robert E W.

Affiliation

Yeung AT; Centre for Microbial Diseases and Immunity Research, University of British Columbia, Vancouver, BC, Canada.

Infect Immun ; 82(3): 1256-67, 2014 Mar.

Article in En | MEDLINE | ID: mdl-24379284

Subject(s)

Bacterial Proteins/genetics; Pseudomonas Infections/genetics; Pseudomonas aeruginosa/genetics; Respiratory Tract Infections/genetics; Respiratory Tract Infections/microbiology; Transcription Factors/genetics; Virulence/genetics; Animals; Bacterial Proteins/metabolism; Dictyostelium/genetics; Dictyostelium/metabolism; Dictyostelium/microbiology; Female; Humans; Lung/metabolism; Lung/microbiology; Macrophages/metabolism; Macrophages/microbiology; Male; Mice; Mice, Inbred C57BL; Mutation/genetics; Neutrophils/metabolism; Neutrophils/microbiology; Phagocytes/metabolism; Phagocytes/microbiology; Pseudomonas Infections/metabolism; Pseudomonas Infections/microbiology; Pseudomonas aeruginosa/metabolism; Rats; Rats, Sprague-Dawley; Respiratory Tract Infections/metabolism; Transcription Factors/metabolism; Transcription, Genetic/genetics; Virulence Factors/genetics; Virulence Factors/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pseudomonas aeruginosa / Pseudomonas Infections / Respiratory Tract Infections / Bacterial Proteins / Transcription Factors / Virulence Type of study: Prognostic_studies Limits: Animals / Female / Humans / Male Language: En Journal: Infect Immun Year: 2014 Document type: Article Affiliation country: Canada

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