Epigenetic drugs as immunomodulators for combination therapies in solid tumors.

Sigalotti, Luca; Fratta, Elisabetta; Coral, Sandra; Maio, Michele

Sigalotti, Luca; Fratta, Elisabetta; Coral, Sandra; Maio, Michele.

Affiliation

Sigalotti L; Cancer Bioimmunotherapy Unit, Centro di Riferimento Oncologico Aviano, National Cancer Institute, Aviano, Italy.
Fratta E; Cancer Bioimmunotherapy Unit, Centro di Riferimento Oncologico Aviano, National Cancer Institute, Aviano, Italy.
Coral S; Medical Oncology and Immunotherapy, Department of Oncology, University Hospital of Siena, Istituto Toscano Tumori, Siena, Italy.
Maio M; Medical Oncology and Immunotherapy, Department of Oncology, University Hospital of Siena, Istituto Toscano Tumori, Siena, Italy. Electronic address: mmaiocro@gmail.com.

Pharmacol Ther ; 142(3): 339-50, 2014 Jun.

Article in En | MEDLINE | ID: mdl-24384533

Subject(s)

Epigenesis, Genetic; Immunologic Factors/therapeutic use; Neoplasms/drug therapy; Animals; Antigen Presentation; Humans; Immunotherapy; Neoplasms/genetics; Neoplasms/immunology; RNA Editing

Key words

DNA methylation; Histone post-translational modifications; Immunostimulatory antibodies; Immunotherapy

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Epigenesis, Genetic / Immunologic Factors / Neoplasms Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Pharmacol Ther Year: 2014 Document type: Article Affiliation country: Italy

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