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Oculopathologic findings in flavivirus-infected gallinaceous birds.
Gamino, V; Escribano-Romero, E; Gutiérrez-Guzmán, A V; Blázquez, A B; Saiz, J C; Höfle, U.
Affiliation
  • Gamino V; SaBio, Instituto de Investigación en Recursos Cinegéticos IREC (CSIC-UCLM-JCCM), Ciudad Real, Spain.
  • Escribano-Romero E; Departamento de Biotecnología, Instituto Nacional de Investigaciones Agrarias INIA, Madrid, Spain.
  • Gutiérrez-Guzmán AV; SaBio, Instituto de Investigación en Recursos Cinegéticos IREC (CSIC-UCLM-JCCM), Ciudad Real, Spain.
  • Blázquez AB; Departamento de Biotecnología, Instituto Nacional de Investigaciones Agrarias INIA, Madrid, Spain.
  • Saiz JC; Departamento de Biotecnología, Instituto Nacional de Investigaciones Agrarias INIA, Madrid, Spain.
  • Höfle U; SaBio, Instituto de Investigación en Recursos Cinegéticos IREC (CSIC-UCLM-JCCM), Ciudad Real, Spain Ursula.hofle@uclm.es.
Vet Pathol ; 51(6): 1113-6, 2014 Nov.
Article in En | MEDLINE | ID: mdl-24395913
Using eye samples of nine 9-week-old experimentally West Nile virus (WNV)-infected red-legged partridges (Alectoris rufa), time course of lesions and WNV antigen appearance in ocular structures were examined. In addition, eye samples of 6 red-legged partridges and 3 common pheasants (Phasianus colchicus) naturally infected with Bagaza virus (BAGV) were used to study lesions and flavivirus antigen distribution in relation to apparent blindness in the former. The rapid onset of microscopic lesions and early presence of viral antigen in the eye of experimentally WNV-infected partridges, prior to the central nervous system involvement, suggested hematogenous spread of the virus into the eye. BAGV-infected partridges had a more pronunced inflammatory reaction and more widespread flavivirus antigen distribution in the retina compared with pheasants and experimentally fatally WNV-infected partridges. Our results suggest that flavivirus replication and development of lesions in ocular structures of gallinaceous game birds vary with the specific virus and host species involved.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bird Diseases / Eye Infections, Viral / Flavivirus Infections / Galliformes / Flavivirus Type of study: Diagnostic_studies Limits: Animals Language: En Journal: Vet Pathol Year: 2014 Document type: Article Affiliation country: Spain Country of publication: United States

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bird Diseases / Eye Infections, Viral / Flavivirus Infections / Galliformes / Flavivirus Type of study: Diagnostic_studies Limits: Animals Language: En Journal: Vet Pathol Year: 2014 Document type: Article Affiliation country: Spain Country of publication: United States