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UWA-121, a mixed dopamine and serotonin re-uptake inhibitor, enhances L-DOPA anti-parkinsonian action without worsening dyskinesia or psychosis-like behaviours in the MPTP-lesioned common marmoset.
Huot, Philippe; Johnston, Tom H; Lewis, Katie D; Koprich, James B; Reyes, M Gabriela; Fox, Susan H; Piggott, Matthew J; Brotchie, Jonathan M.
Affiliation
  • Huot P; Toronto Western Research Institute, Krembil Discovery Tower, 8KD-402, 60 Leonard Street, Toronto, ON M5T 2S8, Canada; Division of Neurology, Movement Disorder Clinic, Toronto Western Hospital, University Health Network, 399 Bathurst Street, Toronto, ON M5T 2S8, Canada. Electronic address: p.huot@umo
  • Johnston TH; Toronto Western Research Institute, Krembil Discovery Tower, 8KD-402, 60 Leonard Street, Toronto, ON M5T 2S8, Canada.
  • Lewis KD; School of Biomedical, Biomolecular and Chemical Sciences, The University of Western Australia, 35 Stirling Highway, Perth 6009, Australia.
  • Koprich JB; Toronto Western Research Institute, Krembil Discovery Tower, 8KD-402, 60 Leonard Street, Toronto, ON M5T 2S8, Canada.
  • Reyes MG; Toronto Western Research Institute, Krembil Discovery Tower, 8KD-402, 60 Leonard Street, Toronto, ON M5T 2S8, Canada.
  • Fox SH; Toronto Western Research Institute, Krembil Discovery Tower, 8KD-402, 60 Leonard Street, Toronto, ON M5T 2S8, Canada; Division of Neurology, Movement Disorder Clinic, Toronto Western Hospital, University Health Network, 399 Bathurst Street, Toronto, ON M5T 2S8, Canada.
  • Piggott MJ; School of Biomedical, Biomolecular and Chemical Sciences, The University of Western Australia, 35 Stirling Highway, Perth 6009, Australia. Electronic address: matthew.piggott@uwa.edu.au.
  • Brotchie JM; Toronto Western Research Institute, Krembil Discovery Tower, 8KD-402, 60 Leonard Street, Toronto, ON M5T 2S8, Canada. Electronic address: brotchie@uhnres.utoronto.ca.
Neuropharmacology ; 82: 76-87, 2014 Jul.
Article in En | MEDLINE | ID: mdl-24447715
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Levodopa / Parkinsonian Disorders / Benzodioxoles / Methylamines / Antiparkinson Agents Type of study: Diagnostic_studies Limits: Animals Language: En Journal: Neuropharmacology Year: 2014 Document type: Article
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Levodopa / Parkinsonian Disorders / Benzodioxoles / Methylamines / Antiparkinson Agents Type of study: Diagnostic_studies Limits: Animals Language: En Journal: Neuropharmacology Year: 2014 Document type: Article