Deletion in the gene BruAb2_0168 of Brucella abortus strains: diagnostic challenges.
Clin Microbiol Infect
; 20(9): O550-3, 2014 Sep.
Article
in En
| MEDLINE
| ID: mdl-24450581
ABSTRACT
Three Brucella abortus strains were isolated from joint hygromas from cows in northern Togo. Two deletions in the 5' side of the gene BruAb2_0168 were identified. As this gene is used for species identification, these deletions have consequences for diagnostic procedures. Multiple locus variable number of tandem repeat (VNTR) analysis was therefore performed for species identification. The strains showed unique VNTR profiles, providing some of the first genotypic data from West Africa. More molecular and epidemiological data are needed from the region, in order to better understand transmission patterns and develop suitable diagnostic assays.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Brucella abortus
/
Cattle Diseases
/
Sequence Deletion
/
Lymphangioma, Cystic
/
Molecular Diagnostic Techniques
/
Genes, Bacterial
Type of study:
Diagnostic_studies
/
Prognostic_studies
Limits:
Animals
Country/Region as subject:
Africa
Language:
En
Journal:
Clin Microbiol Infect
Journal subject:
DOENCAS TRANSMISSIVEIS
/
MICROBIOLOGIA
Year:
2014
Document type:
Article
Affiliation country:
Switzerland