AID downregulation is a novel function of the DNMT inhibitor 5-aza-deoxycytidine.

Tsai, Chiou-Tsun; Yang, Pei-Ming; Chern, Ting-Rong; Chuang, Shu-Hui; Lin, Jung-Hsin; Klemm, Lars; Müschen, Markus; Chen, Ching-Chow

Tsai, Chiou-Tsun; Yang, Pei-Ming; Chern, Ting-Rong; Chuang, Shu-Hui; Lin, Jung-Hsin; Klemm, Lars; Müschen, Markus; Chen, Ching-Chow.

Affiliation

Tsai CT; Department of Pharmacology, College of Medicine, National Taiwan University, Taipei, Taiwan.

Oncotarget ; 5(1): 211-23, 2014 Jan 15.

Article in En | MEDLINE | ID: mdl-24457556

Subject(s)

Azacitidine/analogs & derivatives; Azacitidine/pharmacology; Cytidine Deaminase/metabolism; DNA (Cytosine-5-)-Methyltransferases/antagonists & inhibitors; Enzyme Inhibitors/pharmacology; Animals; DNA (Cytosine-5-)-Methyltransferase 1; Decitabine; Down-Regulation/drug effects; Heterografts; Humans; Mice; Mice, Inbred NOD; Mice, SCID; Molecular Docking Simulation

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Azacitidine / Cytidine Deaminase / DNA (Cytosine-5-)-Methyltransferases / Enzyme Inhibitors Limits: Animals / Humans Language: En Journal: Oncotarget Year: 2014 Document type: Article Affiliation country: Taiwan Country of publication: United States

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