An ancestral non-proteolytic role for presenilin proteins in multicellular development of the social amoeba Dictyostelium discoideum.

Ludtmann, Marthe H R; Otto, Grant P; Schilde, Christina; Chen, Zhi-Hui; Allan, Claire Y; Brace, Selina; Beesley, Philip W; Kimmel, Alan R; Fisher, Paul; Killick, Richard; Williams, Robin S B

Ludtmann, Marthe H R; Otto, Grant P; Schilde, Christina; Chen, Zhi-Hui; Allan, Claire Y; Brace, Selina; Beesley, Philip W; Kimmel, Alan R; Fisher, Paul; Killick, Richard; Williams, Robin S B.

Affiliation

Ludtmann MH; Centre for Biomedical Sciences, School of Biological Sciences, Royal Holloway University of London TW20 0EX, UK.

J Cell Sci ; 127(Pt 7): 1576-84, 2014 Apr 01.

Article in En | MEDLINE | ID: mdl-24463814

Subject(s)

Dictyostelium/metabolism; Presenilin-1/metabolism; Animals; Calcium/metabolism; Cell Membrane/metabolism; Dictyostelium/genetics; Humans; Presenilin-1/biosynthesis; Presenilin-1/genetics; Protozoan Proteins/genetics; Protozoan Proteins/metabolism; Transfection

Key words

Dictyostelium; Presenilin; Î³-secretase

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Dictyostelium / Presenilin-1 Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: J Cell Sci Year: 2014 Document type: Article Affiliation country: United kingdom Country of publication: United kingdom

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