Interferon-Î³ induces leucine-rich repeat kinase LRRK2 via extracellular signal-regulated kinase ERK5 in macrophages.

Kuss, Martin; Adamopoulou, Eleni; Kahle, Philipp J

Kuss, Martin; Adamopoulou, Eleni; Kahle, Philipp J.

Affiliation

Kuss M; Graduate School of Cellular and Molecular Neuroscience, University of Tübingen, Tübingen, Germany; German Center for Neurodegenerative Diseases, University of Tübingen, Tübingen, Germany.

J Neurochem ; 129(6): 980-7, 2014 Jun.

Article in En | MEDLINE | ID: mdl-24479685

Subject(s)

Interferon-gamma/pharmacology; Macrophages/enzymology; Mitogen-Activated Protein Kinase 7/physiology; Protein Serine-Threonine Kinases/biosynthesis; Blotting, Western; Cells, Cultured; Cytokines/metabolism; Enzyme Induction/drug effects; Enzyme Inhibitors/pharmacology; Humans; Immunohistochemistry; Interferon-gamma/antagonists & inhibitors; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Macrophages/drug effects; Mitogen-Activated Protein Kinase 7/antagonists & inhibitors; Real-Time Polymerase Chain Reaction; Signal Transduction/drug effects

Key words

extracellular signal-regulated kinase; interferon; leucine-rich repeat kinase; macrophages; mitogen-activated protein kinase; signal transduction

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Interferon-gamma / Protein Serine-Threonine Kinases / Mitogen-Activated Protein Kinase 7 / Macrophages Type of study: Risk_factors_studies Limits: Humans Language: En Journal: J Neurochem Year: 2014 Document type: Article Affiliation country: Germany Country of publication: United kingdom

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