A novel point mutation of the human glucocorticoid receptor gene causes primary generalized glucocorticoid resistance through impaired interaction with the LXXLL motif of the p160 coactivators: dissociation of the transactivating and transreppressive activities.
J Clin Endocrinol Metab
; 99(5): E902-7, 2014 May.
Article
in En
| MEDLINE
| ID: mdl-24483153
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Pituitary-Adrenal System
/
Receptors, Glucocorticoid
/
Point Mutation
/
Hypothalamo-Hypophyseal System
/
Metabolism, Inborn Errors
Type of study:
Etiology_studies
Limits:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Language:
En
Journal:
J Clin Endocrinol Metab
Year:
2014
Document type:
Article