Integrating influenza antigenic dynamics with molecular evolution.

Bedford, Trevor; Suchard, Marc A; Lemey, Philippe; Dudas, Gytis; Gregory, Victoria; Hay, Alan J; McCauley, John W; Russell, Colin A; Smith, Derek J; Rambaut, Andrew

Bedford, Trevor; Suchard, Marc A; Lemey, Philippe; Dudas, Gytis; Gregory, Victoria; Hay, Alan J; McCauley, John W; Russell, Colin A; Smith, Derek J; Rambaut, Andrew.

Affiliation

Bedford T; Institute of Evolutionary Biology, University of Edinburgh, Edinburgh, United Kingdom.

Elife ; 3: e01914, 2014.

Article in En | MEDLINE | ID: mdl-24497547

Subject(s)

Antigens, Viral/immunology; Evolution, Molecular; Influenza A Virus, H1N1 Subtype/immunology; Influenza A Virus, H3N2 Subtype/immunology; Influenza B virus/immunology; Influenza, Human/virology; Antigens, Viral/genetics; Antigens, Viral/metabolism; Genetic Drift; Genotype; Humans; Influenza A Virus, H1N1 Subtype/genetics; Influenza A Virus, H1N1 Subtype/metabolism; Influenza A Virus, H1N1 Subtype/pathogenicity; Influenza A Virus, H3N2 Subtype/genetics; Influenza A Virus, H3N2 Subtype/metabolism; Influenza A Virus, H3N2 Subtype/pathogenicity; Influenza B virus/genetics; Influenza B virus/metabolism; Influenza B virus/pathogenicity; Influenza Vaccines/immunology; Influenza Vaccines/therapeutic use; Influenza, Human/epidemiology; Influenza, Human/immunology; Influenza, Human/prevention & control; Models, Genetic; Phenotype; Phylogeny; Seasons; Time Factors; Virulence

Key words

Bayesian inference; antigenic cartography; evolution; influenza; multidimensional scaling; phylogenetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Influenza B virus / Evolution, Molecular / Influenza, Human / Influenza A Virus, H1N1 Subtype / Influenza A Virus, H3N2 Subtype / Antigens, Viral Type of study: Prognostic_studies Limits: Humans Language: En Journal: Elife Year: 2014 Document type: Article Affiliation country: United kingdom Country of publication: United kingdom

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