Unexpectedly long 14S ribosomal RNA gene in Tetrahymena mitochondria.
Curr Genet
; 11(6-7): 529-36, 1987.
Article
in En
| MEDLINE
| ID: mdl-2453300
ABSTRACT
Extraction of RNA from Tetrahymena mitochondrial ribosomes yields several RNA species, including a "large" 21S molecule, a "small" 14S molecule, a 7S molecule, and other smaller RNAs. The molecular weight of the 14S rRNA indicates that it is about 1,300 bases in length. We have sequenced the 14S rRNA gene and, by aligning our sequence with that of the corresponding small rRNA from E. coli, find that the 14S rDNA is at least 1,635 bases in length. We propose, based on the results of hybridization studies, that this unexpected length is due to the presence of 7S RNA sequence within the 14S gene sequence. The 7S region is apparently lost from the 14S rRNA, yet is still a component of the ribosome.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Tetrahymena
/
RNA
/
RNA, Ribosomal
/
Genes
/
Mitochondria
Limits:
Animals
/
Humans
Language:
En
Journal:
Curr Genet
Year:
1987
Document type:
Article