NEU1 sialidase regulates the sialylation state of CD31 and disrupts CD31-driven capillary-like tube formation in human lung microvascular endothelia.

Lee, Chunsik; Liu, Anguo; Miranda-Ribera, Alba; Hyun, Sang Won; Lillehoj, Erik P; Cross, Alan S; Passaniti, Antonino; Grimm, P Richard; Kim, Bo-Young; Welling, Paul A; Madri, Joseph A; DeLisser, Horace M; Goldblum, Simeon E

Lee, Chunsik; Liu, Anguo; Miranda-Ribera, Alba; Hyun, Sang Won; Lillehoj, Erik P; Cross, Alan S; Passaniti, Antonino; Grimm, P Richard; Kim, Bo-Young; Welling, Paul A; Madri, Joseph A; DeLisser, Horace M; Goldblum, Simeon E.

Affiliation

Lee C; From the Departments of Medicine.

J Biol Chem ; 289(13): 9121-35, 2014 Mar 28.

Article in En | MEDLINE | ID: mdl-24550400

Subject(s)

Capillaries/cytology; Endothelial Cells/metabolism; Lung/blood supply; N-Acetylneuraminic Acid/metabolism; Neuraminidase/metabolism; Platelet Endothelial Cell Adhesion Molecule-1/metabolism; Animals; Antigens, CD/genetics; Capillaries/physiology; Cell Adhesion; Cell Movement; Endothelial Cells/cytology; Humans; Mice; Neovascularization, Physiologic; Protein Transport; Sialyltransferases/genetics

Key words

Angiogenesis; CD31/PECAM-1; Endothelial Cell; Glycobiology; Neuraminidase; Sialic Acid; Sialidase; Sialoproteins; Sialyltransferase

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Capillaries / N-Acetylneuraminic Acid / Platelet Endothelial Cell Adhesion Molecule-1 / Endothelial Cells / Lung / Neuraminidase Limits: Animals / Humans Language: En Journal: J Biol Chem Year: 2014 Document type: Article Country of publication: United States

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