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Targeting the mevalonate cascade as a new therapeutic approach in heart disease, cancer and pulmonary disease.
Yeganeh, Behzad; Wiechec, Emilia; Ande, Sudharsana R; Sharma, Pawan; Moghadam, Adel Rezaei; Post, Martin; Freed, Darren H; Hashemi, Mohammad; Shojaei, Shahla; Zeki, Amir A; Ghavami, Saeid.
Affiliation
  • Yeganeh B; Hospital for Sick Children Research Institute, Department of Physiology & Experimental Medicine, University of Toronto, Toronto, Canada.
  • Wiechec E; Dept. Clinical & Experimental Medicine, Division of Cell Biology & Integrative Regenerative Med. Center (IGEN), Linköping University, Sweden.
  • Ande SR; Department of Internal Medicine, University of Manitoba, Winnipeg, Manitoba, Canada.
  • Sharma P; Department of Physiology & Pharmacology, Snyder Institute for Chronic Diseases, Faculty of Medicine, University of Calgary, 4C46 HRIC, 3280 Hospital Drive NW, Calgary, Alberta, Canada.
  • Moghadam AR; Scientific Association of Veterinary Medicine, Faculty of Veterinary Medicine, Tabriz Branch, Islamic Azad University, Tabriz, Iran; Young Researchers and Elite Club, Ardabil Branch, Islamic Azad University, Ardabil, Iran.
  • Post M; Hospital for Sick Children Research Institute, Department of Physiology & Experimental Medicine, University of Toronto, Toronto, Canada.
  • Freed DH; Department of Physiology, St. Boniface Research Centre, University of Manitoba, Winnipeg, Canada.
  • Hashemi M; Cellular and Molecular Research Center, Zahedan University of Medical Sciences, Zahedan, Iran.
  • Shojaei S; Department of Biochemistry, Recombinant Protein Laboratory, Medical School, Shiraz University of Medical Sciences, Shiraz, Iran.
  • Zeki AA; U.C. Davis, School of Medicine, U.C. Davis Medical Center, Department of Internal Medicine, Division of Pulmonary, Critical Care, and Sleep Medicine, Center for Comparative Respiratory Biology & Medicine, Davis, CA, USA. Electronic address: amir.zeki@ucdmc.ucdavis.edu.
  • Ghavami S; Department of Human Anatomy and Cell Science, St. Boniface Research Centre, Manitoba Institute of Child Health, Biology of Breathing Theme, University of Manitoba, Winnipeg, Canada. Electronic address: ghavami@cc.umanitoba.ca.
Pharmacol Ther ; 143(1): 87-110, 2014 Jul.
Article in En | MEDLINE | ID: mdl-24582968

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cardiovascular Diseases / Hydroxymethylglutaryl-CoA Reductase Inhibitors / Lung Diseases / Mevalonic Acid / Neoplasms Limits: Animals / Humans Language: En Journal: Pharmacol Ther Year: 2014 Document type: Article Affiliation country: Canada Country of publication: United kingdom

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cardiovascular Diseases / Hydroxymethylglutaryl-CoA Reductase Inhibitors / Lung Diseases / Mevalonic Acid / Neoplasms Limits: Animals / Humans Language: En Journal: Pharmacol Ther Year: 2014 Document type: Article Affiliation country: Canada Country of publication: United kingdom