Antipeptide antibody specific for the N-terminal of soluble immune response suppressor neutralizes concanavalin A and IFN-induced suppressor cell activity in an in vitro cytotoxic T lymphocyte response.

Devens, B H; Semenuk, G; Webb, D R

Devens, B H; Semenuk, G; Webb, D R.

Affiliation

Devens BH; Department of Immunopharmacology, Roche Research Center, Nutley, NJ 07110.

J Immunol ; 141(9): 3148-55, 1988 Nov 01.

Article in En | MEDLINE | ID: mdl-2459244

Subject(s)

Cytotoxicity, Immunologic; Immune Sera/pharmacology; Peptide Fragments/immunology; Suppressor Factors, Immunologic/immunology; T-Lymphocytes, Cytotoxic/immunology; T-Lymphocytes, Regulatory/immunology; Amino Acid Sequence; Animals; Antibody Specificity; Binding, Competitive; Concanavalin A; Cytotoxicity, Immunologic/drug effects; Epitopes/immunology; Interferons; Lymphocyte Activation/drug effects; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Neutralization Tests; Rabbits; Suppressor Factors, Immunologic/physiology

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Collection: 01-internacional Database: MEDLINE Main subject: Peptide Fragments / T-Lymphocytes, Cytotoxic / Suppressor Factors, Immunologic / T-Lymphocytes, Regulatory / Cytotoxicity, Immunologic / Immune Sera Limits: Animals Language: En Journal: J Immunol Year: 1988 Document type: Article Country of publication: United States

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