Rate and extent of leakage of a magnetic resonance contrast agent tend to be lower under isoflurane anesthesia in comparison to halothane in a rat model of embolic stroke.

Bezerra, Francisco J; Brown, Morris; Alarcon, William; Karki, Kishor; Knight, Robert A; Keenan, Kelly A; Nagaraja, Tavarekere N

Bezerra, Francisco J; Brown, Morris; Alarcon, William; Karki, Kishor; Knight, Robert A; Keenan, Kelly A; Nagaraja, Tavarekere N.

Neurol Res ; 36(9): 847-50, 2014 Sep.

Article in En | MEDLINE | ID: mdl-24601723

Subject(s)

Anesthetics, Inhalation/pharmacology; Contrast Media; Halothane/pharmacology; Isoflurane/pharmacology; Magnetic Resonance Imaging/methods; Stroke/physiopathology; Animals; Blood-Brain Barrier/drug effects; Blood-Brain Barrier/physiopathology; Brain Ischemia/pathology; Brain Ischemia/physiopathology; Cerebrovascular Circulation/drug effects; Cerebrovascular Circulation/physiology; Disease Models, Animal; Gadolinium DTPA; Infarction, Middle Cerebral Artery; Intracranial Embolism/pathology; Intracranial Embolism/physiopathology; Male; Rats, Wistar; Stroke/pathology; Time Factors

Key words

ASL-MRI,; Bloodbrain barrier,; DCE-MRI,; Inhalational anesthetics,; Ktrans,; Middle cerebral artery

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Magnetic Resonance Imaging / Anesthetics, Inhalation / Contrast Media / Stroke / Halothane / Isoflurane Type of study: Prognostic_studies Limits: Animals Language: En Journal: Neurol Res Year: 2014 Document type: Article Country of publication: United kingdom

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